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1H-Pyrazole, 3-(chloromethyl)-5-methyl-, hydrochloride (1:) synthesis

4synthesis methods
29004-73-7 Synthesis
5-Methyl-3-methanol-1H-pyrazol [1R-(1,2,5)]

29004-73-7
40 suppliers
$35.00/100mg

1H-Pyrazole, 3-(chloromethyl)-5-methyl-, hydrochloride (1:)

66301-66-4
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Yield:66301-66-4 91%

Reaction Conditions:

with thionyl chloride at 80; for 1 h;

References:

Grotjahn, Douglas B.;Van, Sang;Combs, David;Lev, Daniel A.;Schneider, Christian;Rideout, Marc;Meyer, Christoph;Hernandez, Genaro;Mejorado, Lupe [Journal of Organic Chemistry,2002,vol. 67,# 26,p. 9200 - 9209]