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5-BENZO[1,3]DIOXOL-5-YL-ISOXAZOLE-3-CARBOXYLIC ACID synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: potassium carbonate / tetrahydrofuran; methanol / 2 h / 20 °C
2: triethylamine / N,N-dimethyl-formamide / 17 h / 20 °C / Inert atmosphere
3: water; sodium hydroxide / tetrahydrofuran / 17 h / 20 °C

References:

US2019/330198,2019,A1