ChemicalBook CAS DataBase List (1R)-trans-4-[N-Boc-1-aminoethyl]cyclohexanecarboxylic Acid

(1R)-trans-4-[N-Boc-1-aminoethyl]cyclohexanecarboxylic Acid synthesis

7synthesis methods

Product Name:(1R)-trans-4-[N-Boc-1-aminoethyl]cyclohexanecarboxylic Acid
CAS Number:671815-99-9
Molecular formula:C14H25NO4
Molecular Weight:271.35

24424-99-5 Synthesis

24424-99-5
823 suppliers
$13.50/25G

trans-(R)-4-(1-Aminoethyl)cyclohexanecarboxylic acid

149004-75-1
2 suppliers
inquiry

(1R)-trans-4-[N-Boc-1-aminoethyl]cyclohexanecarboxylic Acid

671815-99-9
25 suppliers
$165.00/10mg

Yield:671815-99-9 89%

Reaction Conditions:

Stage #1: trans-(R)-4-(1-aminoethyl)cyclohexanecarboxylic acidwith sodium hydroxide in tetrahydrofuran;water at 0; for 0.5 h;
Stage #2: di-tert-butyl dicarbonate in tetrahydrofuran;water at 20; for 48 h;
Stage #3: with hydrogenchloride in water; for 3 - 4 h;

References:

Paleek, Jii;Zweigerdt, Robert;Olmer, Ruth;Martin, Ulrich;Kirschning, Andreas;Draeger, Gerald [Organic and Biomolecular Chemistry,2011,vol. 9,# 15,p. 5503 - 5510] Location in patent:experimental part

3886-69-9 Synthesis

3886-69-9
561 suppliers
$14.00/25G

671815-99-9
25 suppliers
$165.00/10mg

References

36283-44-0 Synthesis

36283-44-0
46 suppliers
$85.00/500mg

671815-99-9
25 suppliers
$165.00/10mg

References

88146-37-6 Synthesis

N-[(1R)-1-(4-Acetylphenyl)ethyl]acetamide

88146-37-6
14 suppliers
$112.50/250mg

671815-99-9
25 suppliers
$165.00/10mg

References

4-[(1R)-1-(Acetylamino)ethyl]benzoic Acid

859163-61-4
12 suppliers
$155.00/500mg

671815-99-9
25 suppliers
$165.00/10mg

References