1,2,3,4,5,6,7,8-octahydro-5,5-dimethylnaphthalene-2-carbaldehyde synthesis

Yield:68991-96-8 99%

Reaction Conditions:

with 1-methyl-3-butylimidazolium zinc chloride at 150; under 750.075 Torr; for 2 h;Sealed tube;Inert atmosphere;

Steps:

19-23

10 g of the reaction substrate and 1 g of the [C4mim]Zn2Cl5 catalyst were respectively added to the reaction vessel in a reaction vessel, and after sealing, the nitrogen gas was replaced with nitrogen for five times, and the initial pressure of nitrogen gas was 0.1 MPa.The temperature was raised to 150 ° C, and the reaction was stirred at 1000 rpm for 2 h.After the reaction was completed, the temperature was lowered to room temperature, and the reaction mixture was separated into two layers.The supernatant was poured and sampled for analysis. The remaining lower ionic liquid catalyst was washed three times with n-hexane and used directly for the next reaction, and was reused five times.Qualitative analysis of the product by GC-MS combined with standard and standard control,Quantitative analysis was achieved by gas chromatography internal standard method. The reaction results are shown in Table 3.

References:

CN109651122,2019,A Location in patent:Paragraph 0032-0036