1,4-Naphthalenedione, 2-chloro-3-[[2-(diethylamino)ethyl]amino]- synthesis

Yield:69895-75-6 74%

Reaction Conditions:

with triethylamine in diethyl ether at 20; for 24 h;

Steps:

44 (44) 2-Chloro-3-(2-(diethylamino)ethylamino)-1,4-napthoquinone

2, 3 a-Dichloro provided 1, 4 a-napthoquinone 1g, (4. 4mmol) diethylether 30 ml a melting solution N, N provided diethylethane provided 1, 2 a-diamine 939 micro l (6. 6mmol), triethylamine 610 micro l some excellent. 24 hours at room temperature then evaporated in pressure with respect to the stirring mixture. (Hexanes: EtOAc=20:1) column chromatography compound into a compound having a formula 44 50L positive number (NQ 44) obtained.Yield: 74%

References:

KR101761848,2017,B1 Location in patent:Paragraph 0414-0417