ChemicalBook CAS DataBase List 7-AMINO-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE

7-AMINO-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE synthesis

8synthesis methods

Product Name:7-AMINO-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE
CAS Number:66491-03-0
Molecular formula:C9H10N2O
Molecular Weight:162.19

7-NITRO-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE

22245-96-1
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7-AMINO-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE

66491-03-0
82 suppliers
$74.00/100mg

Yield: 98.7%

Reaction Conditions:

with palladium on activated charcoal;hydrogen in methanol for 3 h;

Steps:

1.1.5 1.5.Preparation of 7-amino-3,4-dihydroisoquinoline-1(2H)-one
7-nitro-3,4-dihydro-isoquinoline -1 (2H) - one (1.88g, 9.8mmol) and Pd / C (190mg) was added to methanol (50 mL), the hydrogenation reaction for 3 hours,Filtration and concentration of the filtrate gave the title compound (1.57 g, yield 98.7%).

References:

Shandong Xuanzhu Pharmaceutical Technology Co., Ltd.;Wang Tingzhong;Chen Bo;Zhu Peng;Liu Bin CN110294742, 2019, A Location in patent:Paragraph 0212; 0225-0227

1196-38-9
165 suppliers
$8.00/100mg

66491-03-0
82 suppliers
$74.00/100mg

References

6970-83-8 Synthesis

6970-83-8
41 suppliers
$34.00/100mg

66491-03-0
82 suppliers
$74.00/100mg

References

91-21-4
255 suppliers
$5.00/5g

66491-03-0
82 suppliers
$74.00/100mg

References

6552-60-9 Synthesis

6552-60-9
16 suppliers
$137.75/1g

66491-03-0
82 suppliers
$74.00/100mg

References