ChemicalBook CAS DataBase List 7-Azaspiro[3.5]nonane-7-carboxylic acid, 2-hydroxy-, 1,1-dimethylethyl ester

7-Azaspiro[3.5]nonane-7-carboxylic acid, 2-hydroxy-, 1,1-dimethylethyl ester synthesis

3synthesis methods

Product Name:7-Azaspiro[3.5]nonane-7-carboxylic acid, 2-hydroxy-, 1,1-dimethylethyl ester
CAS Number:240401-28-9
Molecular formula:C13H23NO3
Molecular Weight:241.33

159635-49-1 Synthesis

tert-Butyl 4-methylenepiperidine-1-carboxylate

159635-49-1
247 suppliers
$5.00/250mg

7-Azaspiro[3.5]nonane-7-carboxylic acid, 2-hydroxy-, 1,1-dimethylethyl ester

240401-28-9
78 suppliers
$45.00/50mg

Yield:-

Steps:

Multi-step reaction with 2 steps
1: zinc/copper couple / 1,2-dimethoxyethane; tert-butyl methyl ether / 15 - 20 °C / Inert atmosphere
2: sodium tetrahydroborate / methanol / 2 h / 0 - 20 °C / Inert atmosphere

References:

BETA PHARMA CANADA INC.;WANG, Zhaoyin;LI, Lianhai;WANG, Zhigang WO2013/13308, 2013, A1

203661-69-2 Synthesis

tert-butyl 2-oxo-7-azaspiro[3.5]nonane-7-carboxylate

203661-69-2
163 suppliers
$8.00/250mg

240401-28-9
78 suppliers
$45.00/50mg

References

396653-31-9 Synthesis

tert-butyl 1,1-dichloro-2-oxo-7-azaspiro[3.5]nonane-7-carboxylate

396653-31-9
14 suppliers
inquiry

240401-28-9
78 suppliers
$45.00/50mg

References