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7-Iodooxindole, 96% synthesis

3synthesis methods
-

Yield:31676-49-0 81%

Reaction Conditions:

Stage #1: 7-iodoisatinwith hydrazine hydrate at 125; for 1 h;
Stage #2: with hydrogenchloride at 60; for 2 h;

References:

Lin, Songnian;Danishefsky, Samuel J. [Angewandte Chemie - International Edition,2001,vol. 40,# 10,p. 1967 - 1970]