7-Methoxy-2-(trifluoromethyl)quinolin-4-ol synthesis
- Product Name:7-Methoxy-2-(trifluoromethyl)quinolin-4-ol
- CAS Number:41192-85-2
- Molecular formula:C11H8F3NO2
- Molecular Weight:243.18
536-90-3
292 suppliers
$10.00/5g
372-31-6
471 suppliers
$5.00/10g
41192-85-2
20 suppliers
$330.00/1g
Yield:41192-85-2 12%
Reaction Conditions:
with polyphosphoric acid at 100 - 120; for 4 h;Conrad-Limpach Synthesis;
References:
Schultz, John R.;Costa, Stephen K.;Jachak, Gorakhnath R.;Hegde, Pooja;Zimmerman, Matthew;Pan, Yan;Josten, Michaele;Ejeh, Chinedu;Hammerstad, Travis;Sahl, Hans Georg;Pereira, Pedro M.;Pinho, Mariana G.;Dartois, Véronique;Cheung, Ambrose;Aldrich, Courtney C. [Journal of Medicinal Chemistry,2022,vol. 65,# 20,p. 13910 - 13934] Location in patent:supporting information