![](/CAS/GIF/1654-34-8.gif)
7-Nitrogramine synthesis
- Product Name:7-Nitrogramine
- CAS Number:1654-34-8
- Molecular formula:C11H13N3O2
- Molecular Weight:219.24
![Formaldehyde](/CAS/GIF/50-00-0.gif)
50-00-0
846 suppliers
$10.00/25g
![7-Nitroindole](/CAS/GIF/6960-42-5.gif)
6960-42-5
250 suppliers
$10.00/1g
![Dimethylamine](/CAS/GIF/124-40-3.gif)
124-40-3
498 suppliers
$18.00/100ml
![7-Nitrogramine](/CAS/GIF/1654-34-8.gif)
1654-34-8
16 suppliers
$375.00/1g
Yield:-
Reaction Conditions:
in water at 20; for 72 h;
Steps:
39.A
A mixture of 7-nitro-lH-indole (3 g, 18.5 mmol), 40% aqueous dimethylamine (3.12 mL, 27.7 mmol) and 37% aqueous formaldehyde (1.57 mL, 19.3 mmol) was stirred for three days at ambient temperature. The reaction mixture was diluted with U2O (20 mL) followed 15% aqueous νaOη (200 mL) and extracted with CηCI3 (3 x 200 mL). The combined organic extracts were dried over νa2SC>4, filtered, and concentrated in vacuo to give the title compound in sufficient purity for use in the next step. MS: r?/z= l81 (M + l).
References:
WO2007/61692,2007,A2 Location in patent:Page/Page column 117
![7-Nitroindole](/CAS/GIF/6960-42-5.gif)
6960-42-5
250 suppliers
$10.00/1g
![N,N,N',N'-TETRAMETHYLDIAMINOMETHANE](/CAS/GIF/51-80-9.gif)
51-80-9
177 suppliers
$21.00/1mL
![7-Nitrogramine](/CAS/GIF/1654-34-8.gif)
1654-34-8
16 suppliers
$375.00/1g