1H-Pyrazole-3-carboxylic acid, 4-aMino-5-phenyl-, ethyl ester synthesis
- Product Name:1H-Pyrazole-3-carboxylic acid, 4-aMino-5-phenyl-, ethyl ester
- CAS Number:70015-76-8
- Molecular formula:C12H13N3O2
- Molecular Weight:231.25
70015-74-6
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70015-76-8
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$80.00/100mg
Yield:70015-76-8 85%
Reaction Conditions:
with hydrogen;palladium 10% on activated carbon in ethanol; under 2327.23 Torr; for 5 h;
Steps:
91.2
Step 2: Preparation of 4-Amino-5-phenyl-2H-pyrazole-3-carboxylic acid ethyl ester (30) To a solution of 4-Nitroso-5-phenyl-2H-pyrazole-3-carboxylic acid ethyl ester 5 (29) (10 g, 40.8 mmol) in ethanol (300 mL) was added 10% Pd-C (7 gm) and the mixture was stirred at room temperature under hydrogen atmosphere (45 Psi H2 atm) for 5 hrs. The mixture was filtered through Celite and concentrated under vacuum to give the desired compound 30(8 gm, 85% yield).
References:
US2006/128729,2006,A1 Location in patent:Page/Page column 108
1224879-11-1
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70015-76-8
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6296-54-4
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70015-76-8
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98-86-2
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70015-76-8
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5814-38-0
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70015-76-8
17 suppliers
$80.00/100mg