(1E)-1-(5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)ETHANONE OXIME synthesis

Yield:7357-12-2 99%

Reaction Conditions:

with hydroxylamine hydrochloride;sodium acetate in ethanol;water; for 3 h;Reflux;

References:

Madsen, Peter;Kodra, János T.;Behrens, Carsten;Nishimura, Erica;Jeppesen, Claus B.;Pridal, Lone;Andersen, Birgitte;Knudsen, Lotte B.;Valcarce-Aspegren, Carmen;Guldbrandt, Mette;Christensen, Inge T.;J?rgensen, Anker S.;Ynddal, Lars;Brand, Christian L.;Bagger, Morten Aa.;Lau, Jesper [Journal of Medicinal Chemistry,2009,vol. 52,# 9,p. 2989 - 3000] Location in patent:supporting information; experimental part