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ChemicalBook CAS DataBase List 2,2-Difluoro-2-[4-(trifluoromethyl)phenyl]acetic Acid

2,2-Difluoro-2-[4-(trifluoromethyl)phenyl]acetic Acid synthesis

6synthesis methods
73789-96-5 Synthesis
ethyl 2,2-difluoro-2-(4-(trifluoromethyl)phenyl)acetate

73789-96-5
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Yield:73790-11-1 79%

Reaction Conditions:

with hydrogen iodide in acetic acid;Heating;

References:

Middleton, W. J.;Bingham, E. M. [Journal of Organic Chemistry,1980,vol. 45,# 14,p. 2883 - 2887]