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[[4-(4-METHOXYPHENYL)-5-METHYL-4H-1,2,4-TRIAZOL-3-YL]THIO]ACETIC ACID synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: pyridine / CHCl3 / 3 h / 0 - 25 °C
2: aq. NaOH / 5 h / Heating
3: triethylamine / CH2Cl2 / 5 h / 25 °C

References:

Wang, Zhiwei;Wu, Baogen;Kuhen, Kelli L.;Bursulaya, Badry;Nguyen, Truc N.;Nguyen, Deborah G.;He, Yun [Bioorganic and Medicinal Chemistry Letters,2006,vol. 16,# 16,p. 4174 - 4177]