ChemicalBook CAS DataBase List N-[1-[2-(4-HYDROXY-PHENYL)-ETHYL]-PIPERIDIN-4-YL]-N-PHENYL-PROPIONAMIDE

N-[1-[2-(4-HYDROXY-PHENYL)-ETHYL]-PIPERIDIN-4-YL]-N-PHENYL-PROPIONAMIDE synthesis

6synthesis methods

Product Name:N-[1-[2-(4-HYDROXY-PHENYL)-ETHYL]-PIPERIDIN-4-YL]-N-PHENYL-PROPIONAMIDE
CAS Number:76107-53-4
Molecular formula:C22H28N2O2
Molecular Weight:352.47

61439-59-6 Synthesis

61439-59-6
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N-[1-[2-(4-HYDROXY-PHENYL)-ETHYL]-PIPERIDIN-4-YL]-N-PHENYL-PROPIONAMIDE

76107-53-4
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Yield:-

Steps:

Multi-step reaction with 3 steps
1: thionyl chloride / CHCl₃ / 3 h / Heating
2: 0.9 g / KI, Na₂CO₃ / various solvent(s) / 48 h / Heating
3: 0.4 g / H₂ / 5percent Pd-C / ethanol

References:

Goromaru;Katashima;Matsuura;Yoshimura [Chemical and Pharmaceutical Bulletin,1985,vol. 33,# 9,p. 3922 - 3928]

7021-11-6 Synthesis