ChemicalBook CAS DataBase List 5-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid

5-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid synthesis

3synthesis methods

Product Name:5-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid
CAS Number:784144-05-4
Molecular formula:C9H5F3N2O2
Molecular Weight:230.1434

127-17-3 Synthesis

127-17-3
517 suppliers
$5.00/10g

3-Chloro-5-(trifluoromethyl)pyridin-2-amine

79456-26-1
285 suppliers
$5.00/1g

5-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid

784144-05-4
38 suppliers
$45.00/10mg

Yield:784144-05-4 97%

Reaction Conditions:

with potassium phosphate;magnesium sulfate;acetic acid;bis(tri-t-butylphosphine)palladium⁽⁰⁾ in N,N-dimethyl acetamide at 140; for 4 h;

References:

Nazare, Marc;Schneider, Claudia;Lindenschmidt, Andreas;Will, David William [Angewandte Chemie - International Edition,2004,vol. 43,# 34,p. 4526 - 4528]

127-17-3 Synthesis

127-17-3
517 suppliers
$5.00/10g

211308-82-6 Synthesis

3-iodo-5-(trifluoromethyl)-2-pyridinylamine

211308-82-6
96 suppliers
$19.00/100mg

784144-05-4
38 suppliers
$45.00/10mg

References

74784-70-6 Synthesis

74784-70-6
324 suppliers
$5.00/1g

784144-05-4
38 suppliers
$45.00/10mg

References