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Cyclohexanecarboxylic acid, 2-(aminomethyl)-, methyl ester synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: tetrabutyl ammonium fluoride / tetrahydrofuran / 17 h / 70 °C
2: hydrogen / methanol / 25.5 h / 20 °C / 2068.65 Torr

References:

Johnson, Matthew R.;Gauuan, Jolicia F.;Guo, Cheng;Guzzo, Peter R.;Le, Van-Duc;Shenoy, Rajesh A.;Hamby, James;Roark, Howard;Stier, Michael;Mangette, John E. [Synthetic Communications,2011,vol. 41,# 18,p. 2769 - 2793]