![](/CAS/20180703/GIF/1146576-61-5.gif)
8-Acetyl-5,6,7,8-tetrahydroquinoline synthesis
- Product Name:8-Acetyl-5,6,7,8-tetrahydroquinoline
- CAS Number:1146576-61-5
- Molecular formula:C11H13NO
- Molecular Weight:175.23
![5,6,7,8-Tetrahydroquinoline](/CAS/GIF/10500-57-9.gif)
10500-57-9
285 suppliers
$6.00/5g
![Acetonitrile](/CAS/GIF/75-05-8.gif)
75-05-8
967 suppliers
$10.00/10g
![8-Acetyl-5,6,7,8-tetrahydroquinoline](/CAS/20180703/GIF/1146576-61-5.gif)
1146576-61-5
14 suppliers
$59.50/1g
Yield: 46%
Reaction Conditions:
Stage #1:5,6,7,8-tetrahydroquinoline with n-butyllithium in tetrahydrofuran at 0;Inert atmosphere;
Stage #2:acetonitrile in tetrahydrofuran at 20;Inert atmosphere;
Stage #3: with sulfuric acid;water in tetrahydrofuran
References:
Wang, Deping;Ding, Ke [Chemical Communications,2009,# 14,p. 1891 - 1893] Location in patent:supporting information; experimental part