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ChemicalBook CAS DataBase List 8-hydroxy-1,6-naphthyridine-7-carboxylic acid
410542-70-0

8-hydroxy-1,6-naphthyridine-7-carboxylic acid synthesis

1synthesis methods
methyl 8-hydroxy-1,6-naphthyridine-7-carboxylate

410542-68-6
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8-hydroxy-1,6-naphthyridine-7-carboxylic acid

410542-70-0
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Yield:410542-70-0 87%

Reaction Conditions:

with lithium hydroxide in methanol; for 18 h;Reflux;

References:

Johns, Brian A.;Weatherhead, Jason G.;Allen, Scott H.;Thompson, James B.;Garvey, Edward P.;Foster, Scott A.;Jeffrey, Jerry L.;Miller, Wayne H. [Bioorganic and Medicinal Chemistry Letters,2009,vol. 19,# 6,p. 1802 - 1806] Location in patent:scheme or table