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ChemicalBook CAS DataBase List 8-METHOXYMETHYL-3-ISOBUTYL-1-METHYLXANTHINE

8-METHOXYMETHYL-3-ISOBUTYL-1-METHYLXANTHINE synthesis

2synthesis methods
54052-67-4 Synthesis
6-AMino-1-isobutyl-3-Methyl-5-nitroso-2,4-pyriMidinedione

54052-67-4
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Yield:-

Steps:

Multi-step reaction with 3 steps
1: 94 percent / H2 / Raney-NiW-2 / methanol / 4 h / 5320 Torr
2: 91 percent / 1.) 100 deg C, 4 h; 2.) 20 deg C, 20 h
3: 69 percent / 12N NaOH / H2O / 2 h / 100 °C

References:

Regnier, Gilbert L.;Guillonneau, Claude G.;Duhault, Jacques L.;Tisserand, Francoise P.;Saint-Romas, Guy;Holstorp, Sophie M. [European Journal of Medicinal Chemistry,1987,vol. 22,p. 243 - 250]

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