8-OXO-8-(4-TRIFLUOROMETHYLPHENYL)OCTANOIC ACID synthesis

3synthesis methods

Product Name:8-OXO-8-(4-TRIFLUOROMETHYLPHENYL)OCTANOIC ACID
CAS Number:362669-50-9
Molecular formula:C15H17F3O3
Molecular Weight:302.29

ETHYL 8-OXO-8-(4-TRIFLUOROMETHYLPHENYL)OCTANOATE

362669-42-9
8 suppliers
$366.00/1g

8-OXO-8-(4-TRIFLUOROMETHYLPHENYL)OCTANOIC ACID

362669-50-9
9 suppliers
$366.00/1g

Yield:362669-50-9 68%

Steps:

18 7-(4-Trifluoromethylbenzoyl)heptanoic acid (50c)

7-(4-Trifluoromethylbenzoyl)heptanoic acid (50c) Following a procedure described above in 50a, but substituting ester 49c for ester 49a, the title compound was obtained as a white solid in 68% yield: ¹H NMR (300 MHz, CDCl₃) δ8.06(d, J=8.1 Hz, 2H), 7.73 (d, J=8.1 Hz, 2H), 3.00(t, J=7.5 Hz, 2H), 2.37 (t, J=7.5 Hz, 2H), 1.76(m, 2H), 1.67 (m, 2H), 1.42 (m, 4H); ¹³C NMR (75.4 MHz, CDCl₃) δ23.75, 24.39, 28.78(2), 33.90, 38.67, 123.69(q, J_CF=272 Hz), 125.62(q, J_CF=3.7 Hz), 128.33, 134.21(q, J_CF=32.6 Hz), 139.59, 180.07, 199.28.

References:

US2002/115826,2002,A1

29823-18-5 Synthesis

29823-18-5
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$9.00/1g

362669-50-9
9 suppliers
$366.00/1g

References

51100-70-0
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inquiry

362669-50-9
9 suppliers
$366.00/1g

References