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8-(TRIFLUOROMETHYL)QUINOLINE-2-CARBALDEHYDE synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 51 percent / 12N aq. HCl / butan-1-ol / 8 h / Heating
2: 81 percent / SeO2 / dioxane / 4 h / Heating

References:

Dade;Provot;Moskowitz;Mayrargue;Prina [Chemical and Pharmaceutical Bulletin,2001,vol. 49,# 4,p. 480 - 483]

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