1-(4-Methoxy-benzyl)-1H-[1,2,3]triazole-4-carboxylic acid ethyl ester synthesis
- Product Name:1-(4-Methoxy-benzyl)-1H-[1,2,3]triazole-4-carboxylic acid ethyl ester
- CAS Number:81581-05-7
- Molecular formula:C13H15N3O3
- Molecular Weight:261.28
70978-37-9
39 suppliers
inquiry
105-37-3
383 suppliers
$10.00/5mL
81581-05-7
18 suppliers
$19.00/100mg
Yield:81581-05-7 95%
Reaction Conditions:
in N,N-dimethyl-formamide at 0 - 20;
Steps:
41
Example 41: Preparation of intermediate 14: ethyl 1-(4-methoxybenzyl)-1H-1,2,3- triazole-4-carboxylateTo a solution of para-methoxy benzyl azide (125.0 g, 0.77 mol) in anhydrous DMF (300 mL) was added dropwise propionic acid ethyl ester (166 g, 1.77 mol) at O0C. After the addition, the mixture was stirred at RT overnight. The mixture was evaporated in vacuo to yield crude title compound (190.0 g, 95.0%) as yellow oil that was used without further purification.
References:
WO2008/4096,2008,A1 Location in patent:Page/Page column 82
70978-37-9
39 suppliers
inquiry
623-47-2
333 suppliers
$10.00/1g
81581-05-7
18 suppliers
$19.00/100mg