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ChemicalBook CAS DataBase List 3-(1-(TERT-BUTOXYCARBONYL)PIPERIDIN-4-YL)BENZOIC ACID

3-(1-(TERT-BUTOXYCARBONYL)PIPERIDIN-4-YL)BENZOIC ACID synthesis

1synthesis methods
585-76-2 Synthesis
3-Bromobenzoic acid

585-76-2
337 suppliers
$6.00/5g

301673-14-3 Synthesis
N-Boc-4-iodopiperidine

301673-14-3
205 suppliers
$10.00/1g

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Yield:-

Reaction Conditions:

with (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride;copper(l) iodide;zinc in N,N-dimethyl acetamide at 85;Negishi coupling reaction;

References:

Tang, Haifeng;Yan, Yan;Feng, Zhe;De Jesus, Reynalda K.;Yang, Lihu;Levorse, Dorothy A.;Owens, Karen A.;Akiyama, Taro E.;Bergeron, Raynald;Castriota, Gino A.;Doebber, Thomas W.;Ellsworth, Kenneth P.;Lassman, Michael E.;Li, Cai;Wu, Margaret S.;Zhang, Bei B.;Chapman, Kevin T.;Mills, Sander G.;Berger, Joel P.;Pasternak, Alexander [Bioorganic and Medicinal Chemistry Letters,2010,vol. 20,# 20,p. 6088 - 6092] Location in patent:scheme or table

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