2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID (4-METHOXY-PHENYL)-AMIDE synthesis
- Product Name:2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID (4-METHOXY-PHENYL)-AMIDE
- CAS Number:83822-33-7
- Molecular formula:C16H18N2O2S
- Molecular Weight:302.39
5382-38-7
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108-94-1
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83822-33-7
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$85.00/250mg
Yield:83822-33-7 79%
Reaction Conditions:
with sulfur;barium aluminate in ethanol;water at 80; for 14 h;Green chemistry;Gewald Aminoheterocycles Synthesis;
Steps:
Typical procedure
General procedure: A mixture of tetrahydrothiopyran-4-one (1 mmol), 2-cyano-Nphenylacetamide (1 mmol), sulfur powder (1.5 mmol) and barium aluminate nanopowder (0.025 g) in EtOH (90% v/v) wasreuxed (80°C) for the appropriate time. The progress of thereaction was monitored by TLC (Table 1). After completion ofthe reaction, the reaction mixture was dissolved in hot ethanol.Simple fltration removed the catalyst. The solvent was concentrated, and recrystallization purifed the crude products fromEtOH.
References:
Yarahmadi, Hossein;Ghashang, Majid;Jabbar Zare, Saeid;Khodaivandi, Alireza [Phosphorus, Sulfur and Silicon and the Related Elements,2017,vol. 192,# 8,p. 945 - 949]
5382-38-7
28 suppliers
inquiry
83822-33-7
26 suppliers
$85.00/250mg