ethyl 5-hydroxy-2,2-dimethyl-3-oxopentanoate(SALTDATA: FREE) synthesis
- Product Name:ethyl 5-hydroxy-2,2-dimethyl-3-oxopentanoate(SALTDATA: FREE)
- CAS Number:84752-35-2
- Molecular formula:C9H16O4
- Molecular Weight:188.22
Yield:84752-35-2 71%
Reaction Conditions:
Stage #1: ethyl 2-bromoisobutyrate;3-Hydroxypropionitrilewith zinc in tetrahydrofuran;Reformatsky-type reaction;
Stage #2: with hydrogenchloride in tetrahydrofuran;
References:
Fuerstner;Mathes;Grela [Chemical Communications,2001,# 12,p. 1057 - 1059]
84752-50-1
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84752-35-2
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84752-35-2
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