5-(2-AMINO-4-METHYLTHIAZOL-5-YL)-2-(METHYLSULFONYL)BENZONITRILE synthesis

2synthesis methods

Product Name:5-(2-AMINO-4-METHYLTHIAZOL-5-YL)-2-(METHYLSULFONYL)BENZONITRILE
CAS Number:847789-31-5
Molecular formula:C12H11N3O2S2
Molecular Weight:293.36

1353878-08-6 Synthesis

1353878-08-6
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5-(2-AMINO-4-METHYLTHIAZOL-5-YL)-2-(METHYLSULFONYL)BENZONITRILE

847789-31-5
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Yield:-

Steps:

Multi-step reaction with 4 steps
1: ammonium acetate / Reflux
2: iron; acetic acid / 100 °C
3: bromine / 1,4-dioxane / 5 - 10 °C
4: ethanol / Reflux

References:

Bruce, Ian;Akhlaq, Mohammed;Bloomfield, Graham C.;Budd, Emma;Cox, Brian;Cuenoud, Bernard;Finan, Peter;Gedeck, Peter;Hatto, Julia;Hayler, Judy F.;Head, Denise;Keller, Thomas;Kirman, Louise;Leblanc, Catherine;Grand, Darren Le;McCarthy, Clive;O'Connor, Desmond;Owen, Charles;Oza, Mrinalini S.;Pilgrim, Gaynor;Press, Nicola E.;Sviridenko, Lilya;Whitehead, Lewis [Bioorganic and Medicinal Chemistry Letters,2012,vol. 22,# 17,p. 5445 - 5450]

218301-22-5 Synthesis

218301-22-5
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847789-31-5
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References