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ChemicalBook CAS DataBase List tert-butyl rac-[(3S,5R)-5-hydroxy-3-piperidinyl]carbamate

tert-butyl rac-[(3S,5R)-5-hydroxy-3-piperidinyl]carbamate synthesis

8synthesis methods
(3S,5R)-(1-Benzyl-5-hydroxy-piperidin-3-yl)-carbamic acid tert-butyl ester

1611481-19-6
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tert-butyl rac-[(3S,5R)-5-hydroxy-3-piperidinyl]carbamate

849161-66-6
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Yield:849161-66-6 95%

Reaction Conditions:

with palladium 10% on activated carbon;hydrogen in methanol at 20; for 1 h;Inert atmosphere;

References:

Orliac, Aurelie;Routier, Julie;Burgat Charvillon, Fabienne;Sauer, Wolfgang H. B.;Bombrun, Agnes;Kulkarni, Santosh S.;Gomez Pardo, Domingo;Cossy, Janine [Chemistry - A European Journal,2014,vol. 20,# 13,p. 3813 - 3824] Location in patent:supporting information