ChemicalBook CAS DataBase List 4-(4-Fluorophenyl)-5-hydroxymethyl-6-isopropyl-2-methylsulfonylpyrimidine

4-(4-Fluorophenyl)-5-hydroxymethyl-6-isopropyl-2-methylsulfonylpyrimidine synthesis

5synthesis methods

Product Name:4-(4-Fluorophenyl)-5-hydroxymethyl-6-isopropyl-2-methylsulfonylpyrimidine
CAS Number:849470-59-3
Molecular formula:C15H17FN2O3S
Molecular Weight:324.37

147118-28-3 Synthesis

Ethyl 4-(4-Fluorophenyl)-6-isopropyl-2-(methylsulfonyl)pyrimidine-5-carboxylate

147118-28-3
16 suppliers
$110.00/5mg

4-(4-Fluorophenyl)-5-hydroxymethyl-6-isopropyl-2-methylsulfonylpyrimidine

849470-59-3
8 suppliers
$120.00/5mg

Yield:849470-59-3 61%

Reaction Conditions:

with diisobutylaluminium hydride in dichloromethane;toluene at -78; for 0.5 h;

References:

Ahmad, Saleem;Madsen, Cort S.;Stein, Philip D.;Janovitz, Evan;Huang, Christine;Ngu, Khehyong;Bisaha, Sharon;Kennedy, Lawrence J.;Chen, Bang-Chi;Zhao, Rulin;Sitkoff, Doree;Monshizadegan, Hossain;Yin, Xiaohong;Ryan, Carol S.;Zhang, Rongan;Giancarli, Mary;Bird, Eileen;Chang, Ming;Chen, Xing;Setters, Robert;Search, Debra;Zhuang, Shaobin;Nguyen-Tran, Van;Cuff, Carolyn A.;Harrity, Thomas;Darienzo, Celia J.;Li, Tong;Reeves, Richard A.;Blanar, Michael A.;Barrish, Joel C.;Zahler, Robert;Robl, Jeffrey A. [Journal of Medicinal Chemistry,2008,vol. 51,# 9,p. 2722 - 2733]

4-(4-Fluorophenyl)-5-hydroxymethyl-6-isopropyl-2-methylthiopyrimidine

895129-11-0
7 suppliers
$350.00/25mg

849470-59-3
8 suppliers
$120.00/5mg

References

Pentanoic acid, 2-[(4-fluorophenyl)methylene]-4-methyl-3-oxo-, ethyl ester

122930-45-4
1 suppliers
inquiry

849470-59-3
8 suppliers
$120.00/5mg

References

7152-15-0 Synthesis

7152-15-0
246 suppliers
$10.00/1g

849470-59-3
8 suppliers
$120.00/5mg

References

147118-27-2 Synthesis

Ethyl 4-(4-Fluorophenyl)-6-isopropyl-2-methylthiopyrimidine-5-carboxylate

147118-27-2
14 suppliers
$498.93/5MG

849470-59-3
8 suppliers
$120.00/5mg

References