2-(4-Fluorophenyl)-1H-benzimidazole-5-carboxylic acid synthesis
- Product Name:2-(4-Fluorophenyl)-1H-benzimidazole-5-carboxylic acid
- CAS Number:850705-30-5
- Molecular formula:C14H9FN2O2
- Molecular Weight:256.23
459-57-4
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850705-30-5
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Yield:-
Steps:
Multi-step reaction with 2 steps
1: disodium metabisulfite; lithium hydroxide monohydrate / ethanol / 0.5 h / 20 °C
2: N,N-dimethyl-formamide / 0.05 h / 240 °C / 7500.75 Torr
References:
Polat, Bilge Uzun;?evik, Ulviye Acar;Dikmen, Miri?;?zkay, Yusuf [Pharmaceutical Chemistry Journal,2022,vol. 56,# 4,p. 451 - 455]