(6-[4-(TRIFLUOROMETHOXY)PHENYL]PYRIDIN-3-YL)METHANOL synthesis
- Product Name:(6-[4-(TRIFLUOROMETHOXY)PHENYL]PYRIDIN-3-YL)METHANOL
- CAS Number:851069-96-0
- Molecular formula:C13H10F3NO2
- Molecular Weight:269.22
![6-[4-(TrifluoroMethoxy)phenyl]-3-pyridinecarbaldehyde](/CAS/GIF/851069-97-1.gif)
851069-97-1
19 suppliers
inquiry
851069-96-0
23 suppliers
inquiry
Yield:851069-96-0 100%
Reaction Conditions:
with sodium tetrahydroborate in ethanol at 0 - 20; for 0.166667 h;
Steps:
9.a
6-(4-Trifluoromethoxy-phenyl)-pyridine-3-carbaldehyde (2.0 g, 7.48 mmol) was dissolved in EtOH (37 ml) and treated at 0° C. with NaBH4 (0.28 g, 7.48 mmol). After 10 min the cooling bath was removed and stirring was continued at ambient temperature. Pouring onto crashed ice, twofold extraction with AcOEt, washing with water, drying over sodium sulfate, and evaporation of the solvents afforded 2.08 g (7.7 mmol, quant.) of the title compound as off-white solid of mp. 57-58° C. MS: 269.1 (M)+.
References:
US2005/96353,2005,A1 Location in patent:Page/Page column 26
139301-27-2
382 suppliers
$14.00/5G
851069-96-0
23 suppliers
inquiry
149806-06-4
416 suppliers
$5.00/1g
851069-96-0
23 suppliers
inquiry