4-(MORPHOLINE-4-SULFONYL)-BENZYLAMINE HYDROCHLORIDE synthesis
- Product Name:4-(MORPHOLINE-4-SULFONYL)-BENZYLAMINE HYDROCHLORIDE
- CAS Number:852399-79-2
- Molecular formula:C11H16N2O3S
- Molecular Weight:256.32
10254-89-4
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852399-79-2
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Yield:852399-79-2 74%
Reaction Conditions:
with hydrogen in methanol at 20; under 760.051 Torr; for 0.333333 h;
Steps:
294.1 Step 1 . [4-(Morpholine-4-sulfonyl)phenyl]methanamine.
A mixture of 4- (morpholine-4-sulfonyl)benzonitrile (200 mg, 0.79 mmol, 1 .00 equiv) and Raney Ni (2 g) in MeOH (30 mL) was stirred at rt under 1 atmosphere of H2 for 20 min. The catalyst was removed by filtration. The filtrate was concentrated under vacuum to give 0.1 5 g (74%) of [4-(morpholine-4-sulfonyl)phenyl]methanamine as a light yellow solid. LC/MS (Method F, ESI): RT = 0.91 min, m/z = 257,0 [M+H] + .
References:
WO2013/127266,2013,A1 Location in patent:Page/Page column 168
49584-26-1
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852399-79-2
18 suppliers
$264.00/100mg