Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List 4-HYDROXY-6-METHYL-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER

4-HYDROXY-6-METHYL-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER synthesis

5synthesis methods
-

Yield:85418-82-2 86%

Reaction Conditions:

in diphenylether at 225; for 0.0833333 h;Microwave irradiation;

Steps:

1 3.1.1. General method for the preparation of compounds 3 and 4

General procedure: Method 2. The mixture of the corresponding aniline (10 mmol)and diethyl ethoxymethylene malonate (10 mmol) in diphenyl ether (4 mL) was irradiated in monomod microwave reactor inclosed vessel at 225 C, 200 W, for 5 min. The white solid formedwas filtered off, washed with hexane and purified through recrystallizationfrom DMF to give corresponding compound.

References:

Mermer, Arif;Demirba?, Neslihan;?irin, Yakup;Uslu, Harun;?zdemir, Zeynep;Demirba?, Ahmet [Bioorganic Chemistry,2018,vol. 78,p. 236 - 248]

4-HYDROXY-6-METHYL-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Related Search: