3-(8-chloro-1-(2-phenylquinolin-7-yl)iMidazo[1,5-a]pyrazin-3-yl)cyclobutanone synthesis

Yield:867165-62-6 17.7 g

Reaction Conditions:

with sodium periodate in tetrahydrofuran;water at 20; for 4 h;

References:

Mulvihill, Mark J.;Ji, Qun-Sheng;Coate, Heather R.;Cooke, Andrew;Dong, Hanqing;Feng, Lixin;Foreman, Kenneth;Rosenfeld-Franklin, Maryland;Honda, Ayako;Mak, Gilda;Mulvihill, Kristen M.;Nigro, Anthony I.;O'Connor, Matthew;Pirrit, Caroline;Steinig, Arno G.;Siu, Kam;Stolz, Kathryn M.;Sun, Yingchuan;Tavares, Paula A.R.;Yao, Yan;Gibson, Neil W. [Bioorganic and Medicinal Chemistry,2008,vol. 16,# 3,p. 1359 - 1375]