2-Cyanopyridine-3-boronic acid neopentyl glycol ester synthesis
- Product Name:2-Cyanopyridine-3-boronic acid neopentyl glycol ester
- CAS Number:868944-75-6
- Molecular formula:C11H13BN2O2
- Molecular Weight:216.04
100-70-9
403 suppliers
$13.00/25g
126-30-7
610 suppliers
$8.00/100g
868944-75-6
34 suppliers
$160.00/2.5g
Yield:868944-75-6 94%
Reaction Conditions:
Stage #1: 2-Cyanopyridinewith 2,2,6,6-tetramethyl-piperidine;n-butyllithium;Triisopropyl borate in tetrahydrofuran at -78 - 20;
Stage #2: 2,2-Dimethyl-1,3-propanediolwith acetic acid in tetrahydrofuran at 20; for 1 h;
References:
Hansen, Henriette M.;Lysén, Morten;Begtrup, Mikael;Kristensen, Jesper L. [Tetrahedron,2005,vol. 61,# 42,p. 9955 - 9960]