3-methoxy-N-(1-methylpiperidin-4-yl)-4-nitrobenzamide synthesis
2synthesis methods
- Product Name:3-methoxy-N-(1-methylpiperidin-4-yl)-4-nitrobenzamide
- CAS Number:876126-59-9
- Molecular formula:C14H19N3O4
- Molecular Weight:293.32
Yield:876126-59-9 90%
Reaction Conditions:
with O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate;triethylamine in N,N-dimethyl-formamide at 20; for 16 h;Inert atmosphere;
References:
Chen, Lijia;Yap, Jeremy L.;Yoshioka, Makoto;Lanning, Maryanna E.;Fountain, Rachel N.;Raje, Mithun;Scheenstra, Jacob A.;Strovel, Jeffrey W.;Fletcher, Steven [ACS Medicinal Chemistry Letters,2015,vol. 6,# 7,p. 764 - 769] Location in patent:supporting information