(R)-tert-Butyl 1-(cyclohexylmethyl)pyrrolidin-3-ylcarbamate synthesis
1synthesis methods
- Product Name:(R)-tert-Butyl 1-(cyclohexylmethyl)pyrrolidin-3-ylcarbamate
- CAS Number:876160-15-5
- Molecular formula:C16H30N2O2
- Molecular Weight:282.42
Yield:876160-15-5 80%
Reaction Conditions:
with sodium cyanoborohydride;acetic acid in dichloromethane at 20;
References:
Beghyn, Terence B.;Charton, Julie;Leroux, Florence;Henninot, Antoine;Reboule, Irena;Cos, Paul;Maes, Louis;Deprez, Benoit [Journal of Medicinal Chemistry,2012,vol. 55,# 3,p. 1274 - 1286] Location in patent:experimental part