ChemicalBook CAS DataBase List 6-TRIFLUOROMETHYL-1H-INDAZOLE-3-CARBOXYLIC ACID METHYL ESTER

6-TRIFLUOROMETHYL-1H-INDAZOLE-3-CARBOXYLIC ACID METHYL ESTER synthesis

3synthesis methods

Product Name:6-TRIFLUOROMETHYL-1H-INDAZOLE-3-CARBOXYLIC ACID METHYL ESTER
CAS Number:877773-17-6
Molecular formula:C10H7F3N2O2
Molecular Weight:244.17

121-17-5 Synthesis

121-17-5
7 suppliers
$19.00/250g

6-TRIFLUOROMETHYL-1H-INDAZOLE-3-CARBOXYLIC ACID METHYL ESTER

877773-17-6
37 suppliers
$156.00/50mg

Yield:-

Steps:

Multi-step reaction with 4 steps
1: potassium tert-butylate / tert-butyl alcohol / Reflux
2: dimethyl sulfoxide; sodium chloride / water / 120 °C
3: hydrogen / 5% Pd(II)/C(eggshell) / toluene / 20 °C / 760.05 Torr
4: tert.-butylnitrite; acetic acid / 2.17 h / 90 - 95 °C / Cooling with ice

References:

WO2011/5759,2011,A2

290825-52-4 Synthesis

Dimethyl [2-nitro-4-(trifluoromethyl)phenyl]malonate

290825-52-4
28 suppliers
$42.00/500mg

877773-17-6
37 suppliers
$156.00/50mg

References

methyl (2-nitro-4-trifluorobenzyl)acetate

13544-07-5
30 suppliers
$32.00/500mg

877773-17-6
37 suppliers
$156.00/50mg

References

6-TRIFLUOROMETHYL-1H-INDAZOLE-3-CARBOXYLIC ACID METHYL ESTER Related Search:

6-(TRIFLUOROMETHYL)-1H-INDAZOLE 6-METHYL-3-INDAZOLECARBOXYLIC ACID METHYL ESTER 1H-INDAZOLE-3-CARBOXYLIC ACID METHYL ESTER