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7-Chloro-1,3,5-trimethyl-1H-pyrazolo[4,3-d]pyrimidine synthesis

4synthesis methods
59023-33-5 Synthesis
1,3,5-trimethyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one

59023-33-5
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7-Chloro-1,3,5-trimethyl-1H-pyrazolo[4,3-d]pyrimidine

89239-22-5
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Yield:89239-22-5 98%

Reaction Conditions:

with phosphorus pentachloride;trichlorophosphate for 7 h;Heating;

References:

DeWald;Beeson;Hershenson;Wise;Downs;Heffner;Coughenour;Pugsley [Journal of Medicinal Chemistry,1988,vol. 31,# 2,p. 454 - 461]