![](/CAS/GIF/89460-20-8.gif)
Imidaprilat Benzyl Ester, (Carbonylimidazolidine)tert-butyl Ester synthesis
- Product Name:Imidaprilat Benzyl Ester, (Carbonylimidazolidine)tert-butyl Ester
- CAS Number:89460-20-8
- Molecular formula:C29H37N3O6
- Molecular Weight:523.62
Yield:89460-20-8 82.3%
Steps:
5.1 EXAMPLE 5
(1) t-Butyl (4S)-1-methyl-3-[(2R)-2-(p-toluenesulfonyloxy)propionyl]-2-oxoimidazolidine-4-carboxylate (1 g) obtained in Example 1 - (1) and benzyl (2S)-2-amino-4-phenylbutyrate (1.55 g) were treated similarly as in Example 1 - (2) to give t-butyl (4S)-1-methyl-3-{(2S)-2-[N-((1S)-1-benzyloxycarbonyl-3-phenyl-propyl)amino]propionyl}-2-oxoimidazolidine-4-carboxylate (1.01 g) as colorless syrup. Yield: 82.3%. Maleic acid salt of this product: m.p.: 108°-112° C. [α]D25: -57.4° (C=1, ethanol).
References:
US5013845,1991,A
![(S)-2-Oxo-iMidazolidine-1,5-dicarboxylic acid 1-benzyl ester 5-tert-butyl ester](/CAS/20150408/GIF/77999-24-7.gif)
77999-24-7
10 suppliers
inquiry
![Imidaprilat Benzyl Ester, (Carbonylimidazolidine)tert-butyl Ester](/CAS/GIF/89460-20-8.gif)
89460-20-8
8 suppliers
inquiry
![(S)-3-Methyl-2-oxo-iMidazolidine-1,5-dicarboxylic acid 1-benzyl ester 5-tert-butyl ester](/CAS/20150408/GIF/83056-78-4.gif)
83056-78-4
14 suppliers
inquiry
![Imidaprilat Benzyl Ester, (Carbonylimidazolidine)tert-butyl Ester](/CAS/GIF/89460-20-8.gif)
89460-20-8
8 suppliers
inquiry
![2-bromo-4-phenylbutyric acid](/CAS/GIF/16503-46-1.gif)
16503-46-1
40 suppliers
inquiry
![Imidaprilat Benzyl Ester, (Carbonylimidazolidine)tert-butyl Ester](/CAS/GIF/89460-20-8.gif)
89460-20-8
8 suppliers
inquiry
![DL-Homophenylalanine](/CAS/GIF/1012-05-1.gif)
1012-05-1
202 suppliers
$11.00/5g
![Imidaprilat Benzyl Ester, (Carbonylimidazolidine)tert-butyl Ester](/CAS/GIF/89460-20-8.gif)
89460-20-8
8 suppliers
inquiry