1-((2-(4-chlorophenyl)-5-methyloxazol-4-yl)methyl)piperidine-4-carboxylicacid synthesis

3synthesis methods

Product Name:1-((2-(4-chlorophenyl)-5-methyloxazol-4-yl)methyl)piperidine-4-carboxylicacid
CAS Number:897765-44-5
Molecular formula:C17H19ClN2O3
Molecular Weight:334.8

104-88-1 Synthesis

104-88-1
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1-((2-(4-chlorophenyl)-5-methyloxazol-4-yl)methyl)piperidine-4-carboxylicacid

897765-44-5
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Yield:-

Steps:

Multi-step reaction with 3 steps
1: hydrogenchloride / acetic acid; 1,4-dioxane / 16 h / 0 - 20 °C
2: trichlorophosphate / 1,2-dichloro-ethane / 0.5 h / Reflux
3: potassium hydroxide / ethanol / 16 h / 20 °C

References:

He, Shanshan;Li, Kelin;Lin, Billy;Hu, Zongyi;Xiao, Jingbo;Hu, Xin;Wang, Amy Q.;Xu, Xin;Ferrer, Marc;Southall, Noel;Zheng, Wei;Aubé, Jeffrey;Schoenen, Frank J.;Marugan, Juan J.;Liang, T. Jake;Frankowski, Kevin J. [Journal of Medicinal Chemistry,2017,vol. 60,# 14,p. 6364 - 6383]

498-94-2 Synthesis

498-94-2
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4-CHLOROMETHYL-2-(4-CHLORO-PHENYL)-5-METHYL-OXAZOLE

832076-92-3
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897765-44-5
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References

Oxazole, 2-(4-chlorophenyl)-4,5-dimethyl-, 3-oxide

109544-27-6
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897765-44-5
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References