Ethanol, 2,2'-[(1R)-[1,1'-binaphthalene]-2,2'-diylbis(oxy)]bis- synthesis

5synthesis methods

Product Name:Ethanol, 2,2'-[(1R)-[1,1'-binaphthalene]-2,2'-diylbis(oxy)]bis-
CAS Number:89920-45-6
Molecular formula:C24H22O4
Molecular Weight:374.43

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602-09-5 Synthesis

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Ethanol, 2,2'-[(1R)-[1,1'-binaphthalene]-2,2'-diylbis(oxy)]bis-

89920-45-6
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Yield:89920-45-6 266.6 g

Reaction Conditions:

with potassium hydroxide in water;isopropyl alcohol at 20 - 90; under 3750.38 Torr; for 3 h;Autoclave;Inert atmosphere;Sealed tube;Solvent;Concentration;Temperature;Reagent/catalyst;

Steps:

1-12; 1-4 Comparative Example 1

50.0 g (0.17 mol) of '1,1'-bi-2-naphthol, 200.0 g of a 30% by mass aqueous solution of isopropanol and 0.10 g of potassium hydroxide as a catalyst were charged into a 1 L autoclave and sealed.Next, the inside of the autoclave is kept at 20 to 30 ° C.The inside of the autoclave was replaced with nitrogen. The inside of the autoclave was heated to 90 ° C. (at this time, it was confirmed that 1,1′-bi-2-naphthol was in an undissolved state), and ethylene oxide was adjusted so that the pressure inside the autoclave did not exceed 0.5 MPa. Was introduced into an autoclave in an amount of 19.2 g (0.44 mol). Thereafter, the alkylene oxide addition reaction was allowed to proceed under the reaction conditions of a reaction temperature of 90 ° C. and a reaction time of 3 hours. After the completion of the reaction, the content of the autoclave was cooled to 50 ° C. or lower to obtain 258.9 g of a reaction product.

References:

JP2020/33323,2020,A Location in patent:Paragraph 0064-0079

96-49-1 Synthesis