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ChemicalBook CAS DataBase List 9-HYDRAZINOACRIDINE

9-HYDRAZINOACRIDINE synthesis

2synthesis methods
-

Yield:-

Reaction Conditions:

with hydrazineReflux;

Steps:

Synthesis of aminoalkylamino acridine derivatives(6a-f)

General procedure: To 9-chloroacridine 4 (0.12 g, 1 mmol) was added an excessamount of appropriate amines 5a-f (3 mmol); then, the reactionmixture was refluxed for 1-2 h, until the complete consumptionof the starting materials occurred as monitoredby TLC. The mixture was cooled and poured into ice water,filtered off and dried to yield the desired product 6a-f.

References:

Ahmed, Abdullah A. S.;Awad, Hanem M.;El-Sayed, Ibrahim El-Tantawy;El Gokha, Ahmed A. [Journal of the Iranian Chemical Society,2020,vol. 17,# 5,p. 1211 - 1221]

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