ChemicalBook CAS DataBase List 9-Phenylacridine

9-Phenylacridine synthesis

11synthesis methods

Product Name:9-Phenylacridine
CAS Number:602-56-2
Molecular formula:C19H13N
Molecular Weight:255.31

1207-69-8 Synthesis

1207-69-8
195 suppliers
$13.00/250mg

98-80-6 Synthesis

98-80-6
733 suppliers
$5.00/5g

602-56-2
167 suppliers
$10.00/1g

Yield:602-56-2 96.8%

Reaction Conditions:

with tetrakis(triphenylphosphine) palladium⁽⁰⁾;sodium carbonate in water;toluene at 40; for 3 h;

Steps:

1 Example 1
In a 250 mL three-necked flask, 21.4 g (0.1 mol) of 9-chloroacridine, 14.6 g (0.12 mol) of phenylboronic acid, 0.11 g of Pd (PPh3) 4 catalyst, 100 g of toluene, 2 g of sodium carbonate, and 18 g of deionized water were sequentially added. , Heated to 40 ° C., reacted for 3 hours, cooled to 25 ° C., removed the solvent by rotary evaporation, washed with 100 g of methanol and dispersed, and filtered to obtain a crude product. The crude product was purified with 80 g of toluene and dried to obtain 24.7 g of the product, a yield of 96.8%. HPLC The content is 99.65%.

References:

Weisipu New Materials (Suzhou) Co., Ltd.;Chen Xiao;Yuan Xiaodong;Liu Haifeng;Yu Limin;Chen Hua CN110423220, 2019, A Location in patent:Paragraph 0030; 0031

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