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ChemicalBook CAS DataBase List 2-(2,7-Difluoro-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic Acid

2-(2,7-Difluoro-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic Acid synthesis

6synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 67 percent / 2,6-lutidine / CH2Cl2 / 20 °C
2: aq. hypoxanthine; xanthine oxidase / dimethylsulfoxide; various solvent(s) / 37 °C / pH 7.4

References:

Maeda, Hatsuo;Yamamoto, Kayoko;Nomura, Yoko;Kohno, Iho;Hafsi, Leila;Ueda, Noritsugu;Yoshida, Shoko;Fukuda, Masako;Fukuyasu, Yuka;Yamauchi, Yuji;Itoh, Norio [Journal of the American Chemical Society,2005,vol. 127,# 1,p. 68 - 69]