914606-88-5 synthesis
- Product Name:914606-88-5
- CAS Number:914606-88-5
- Molecular formula:C18H22BNO4S
- Molecular Weight:359.25
98-09-9
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214360-73-3
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914606-88-5
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Yield:914606-88-5 72%
Reaction Conditions:
with pyridine in dichloromethane at 20;Inert atmosphere;
Steps:
General procedure J:
General procedure: (for the synthesis of compounds 28, 36a-36e, 40a-40b) A solution amino-substituted phenylboronic acidpinacolate ester (10 mmol) in DCM (50 mL) was treated with sulfonylchloride (10.5 mmol), followed by pyridine (870 mg,11 mmol)at room temperature under an atmosphere of nitrogen and stirredovernight. After evaporation to dryness, the target compoundswere purified by flash column chromatography.
References:
Qu, Bingxue;Xu, Yongjin;Lu, Yang;Zhuang, Weihao;Jin, Xinxin;Shi, Qiuqiu;Yan, Shike;Guo, Yu;Shen, Zheyuan;Che, Jinxin;Wu, Yize;Tong, Lexian;Dong, Xiaowu;Yang, Haiyan [European Journal of Medicinal Chemistry,2022,vol. 235,art. no. 114257]
