ChemicalBook CAS DataBase List 3-CYANO-4-OXO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

3-CYANO-4-OXO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER synthesis

2synthesis methods

Product Name:3-CYANO-4-OXO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
CAS Number:914988-10-6
Molecular formula:C11H16N2O3
Molecular Weight:224.26

24424-99-5 Synthesis

24424-99-5
821 suppliers
$13.50/25G

3-CYANO-4-OXO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

914988-10-6
89 suppliers
inquiry

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: sodium hydroxide / methanol / 6 h / 70 °C
1.2: 6 h / 0 - 20 °C
2.1: sodium hydride / toluene / 5 h / 80 - 100 °C

References:

GENENTECH, INC.;CONSTELLATION PHARMACEUTICALS, INC.;ROMERO, F. Anthony;MAGNUSON, Steven;PASTOR, Richard;TSUI, Vickie Hsiao-Wei;MURRAY, Jeremy;CRAWFORD, Terry;ALBRECHT, Brian, K.;COTE, Alexandre;TAYLOR, Alexander, M.;LAI, Kwong Wah;CHEN, Kevin, X.;BRONNER, Sarah;ADLER, Marc;EGEN, Jackson;LIAO, Jiangpeng;WANG, Fei;CYR, Patrick;ZHU, Bing-Yan;KAUDER, Steven WO2016/86200, 2016, A1

ethyl 3-(tert-butoxycarbonyl(2-cyanoethyl)aMino)propanoate

266353-22-4
8 suppliers
inquiry

914988-10-6
89 suppliers
inquiry

References

3-CYANO-4-OXO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER Related Search:

tert-butyl (3S,4R)-4-aMino-3-fluoropiperidine-1-carboxylate 1-Piperidinecarboxylicacid,4-hydroxy-2-methyl-,1,1-dimethylethylester,(2S,4R)-(9CI)