ChemicalBook CAS DataBase List 5,6-Dihydroimidazo[4,5,1-jk][1]benzazepine-2,7(1H,4H)-dione

5,6-Dihydroimidazo[4,5,1-jk][1]benzazepine-2,7(1H,4H)-dione synthesis

6synthesis methods

Product Name:5,6-Dihydroimidazo[4,5,1-jk][1]benzazepine-2,7(1H,4H)-dione
CAS Number:92260-81-6
Molecular formula:C11H10N2O2
Molecular Weight:202.21

52099-72-6 Synthesis

52099-72-6
206 suppliers
$5.00/250mg

5,6-Dihydroimidazo[4,5,1-jk][1]benzazepine-2,7(1H,4H)-dione

92260-81-6
79 suppliers
$85.00/25mg

Yield:-

Steps:

Multi-step reaction with 4 steps
1.1: potassium carbonate / acetone / 18 h / Heating / reflux
2.1: sodium hydroxide; water / tetrahydrofuran / 20 °C / Heating / reflux
2.2: 0.5 h / 2 °C
3.1: hydrogenchloride; water / tetrahydrofuran / 2 h
4.1: thionyl chloride / dichloromethane / 2 h / 20 °C
4.2: 20 °C / Heating / reflux

References:

PFIZER LIMITED WO2008/44127, 2008, A1

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3273-68-5 Synthesis