ChemicalBook CAS DataBase List N-[2-[3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-quinoxalinecarboxamide

N-[2-[3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-quinoxalinecarboxamide synthesis

8synthesis methods

Product Name:N-[2-[3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-quinoxalinecarboxamide
CAS Number:925434-55-5
Molecular formula:C25H23N7OS
Molecular Weight:469.56

6851-99-6 Synthesis

6851-99-6
161 suppliers
$12.00/1g

N-[2-[3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-quinoxalinecarboxamide

925434-55-5
54 suppliers
$95.00/10 mg

Yield:-

Steps:

Multi-step reaction with 7 steps
1.1: butanone / 18 h / Heating / reflux
2.1: sodium hydroxide; water / tetrahydrofuran / 18 h / 20 °C
3.1: 4-methyl-morpholine; isobutyl chloroformate / tetrahydrofuran / 3 h / 0 °C
3.2: 0.75 h / 0 °C
4.1: triethylamine / dichloromethane / 0.25 h / 20 °C
5.1: triethylamine / acetonitrile / 24 h / 20 °C
5.2: 24 h / Heating / reflux
6.1: pyridine / 0.17 h / 160 °C / microwave irradiation
7.1: trifluoroacetic acid / dichloromethane / 2 h

References:

SIRTRIS PHARMACEUTICALS, INC. WO2008/156866, 2008, A1

925436-46-0 Synthesis