ChemicalBook CAS DataBase List 2-AMino-4-(3-broMo-phenyl)-6-(4-fluoro-2-MethoxyMethoxy-phenyl)-nicotinonitrile

2-AMino-4-(3-broMo-phenyl)-6-(4-fluoro-2-MethoxyMethoxy-phenyl)-nicotinonitrile synthesis

1synthesis methods

Product Name:2-AMino-4-(3-broMo-phenyl)-6-(4-fluoro-2-MethoxyMethoxy-phenyl)-nicotinonitrile
CAS Number:925923-84-8
Molecular formula:C20H15BrFN3O2
Molecular Weight:428.25

3132-99-8 Synthesis

3132-99-8
476 suppliers
$5.00/10g

1-(4-Fluoro-2-MethoxyMethoxy-phenyl)-ethanone

925922-96-9
4 suppliers
inquiry

109-77-3 Synthesis

109-77-3
426 suppliers
$10.00/5g

2-AMino-4-(3-broMo-phenyl)-6-(4-fluoro-2-MethoxyMethoxy-phenyl)-nicotinonitrile

925923-84-8
9 suppliers
inquiry

Yield:925923-84-8 30%

Reaction Conditions:

with ammonium acetate in toluene; for 18 h;Reflux;

References:

Kobayashi, Toshitake;Sasaki, Satoshi;Tomita, Naoki;Fukui, Seiji;Nakayama, Masaharu;Kiba, Atsushi;Kusaka, Masami;Matsumoto, Shin-Ichi;Yamaguchi, Masashi;Itoh, Fumio;Baba, Atsuo [Bioorganic and Medicinal Chemistry,2010,vol. 18,# 14,p. 5157 - 5171] Location in patent:experimental part